Combining Laravel with React is a powerful way to create full-stack web applications. Laravel handles backend tasks such as authentication, routing, and database management, while React provides a dynamic front-end experience. Integrating APIs between Laravel and React allows for smooth data flow and real-time updates. Using tools like Tailwind CSS, developers can also design responsive and beautiful UIs. Full-stack projects with Laravel and React are perfect for portfolios because they showcase both front-end and back-end skills.